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High Purity Intermediates

Oncology Intermediates Sourcing Solutions

Pharmabridge supplies quality-driven pharmaceutical and botanical intermediates supporting synthetic pathways for key oncology formulations, including Lenalidomide, Methotrexate, Irinotecan, and Etoposide.

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Specific Compounds & Materials

Featured Products in Oncology Intermediates

All ingredients supported with CoA, GMP, and regulatory documentation.
CAS 6559-91-7 Podophyllum-derived High Purity Grade

4′-Demethyl Epipodophyllotoxin Intermediate

4′-Demethyl Epipodophyllotoxin is a key podophyllotoxin-derived intermediate used in the synthesis of Etoposide and related epipodophyllotoxin anticancer derivatives.

Purity / Assay: ≥ 98.0%
Appearance: Off-White Powder
COA NMR & HPLC Reports Technical Specification
CAS 84650-63-5 Standardized Alkaloid Extract Grade

Vinca Extract (Catharanthus roseus Botanical Intermediate)

Vinca Extract derived from Catharanthus roseus (Vinca rosea) provides naturally occurring starting alkaloids for the production of Vinblastine, Vincristine, and Vinorelbine.

Purity / Assay: Standardized for Total Vinca Alkaloids
Appearance: Brownish Fine Powder
COA HPLC Fingerprint Botanical Origin Certificate
CAS 7689-03-4 Pharmaceutical Grade Intermediates

Camptothecin (CPT) & 7-Ethyl-10-Hydroxycamptothecin (SN-38)

Camptothecin (CPT from Camptotheca acuminata) and SN-38 (7-Ethyl-10-Hydroxycamptothecin) are key structural starting materials for the manufacturing route of Irinotecan.

Purity / Assay: ≥ 98.0%
Appearance: Pale Yellow Powder
COA HPLC Assay Spectral Data
CAS 24666-56-6 / 98475-07-1 Pharma Synthesis Grade

Lenalidomide Intermediates (3-Aminopiperidine-2,6-dione HCl & Methyl 2-Bromomethyl-3-nitrobenzoate)

Pharmabridge supplies key synthetic intermediates for Lenalidomide immunomodulatory oncology API synthesis: 3-Aminopiperidine-2,6-dione HCl (CAS 24666-56-6) and Methyl 2-(bromomethyl)-3-nitrobenzoate (CAS 98475-07-1).

Purity / Assay: ≥ 98.5%
Appearance: Crystalline Powder
COA Batch Analytical Reports MSDS
CAS 1118-89-4 / 5392-28-9 / 7413-34-5 Comprehensive Synthetic Range

Methotrexate Intermediates Portfolio (7 Key Building Blocks)

Comprehensive range of 7 Methotrexate building blocks: L-Glutamic Acid Diethyl Ester HCl (CAS 1118-89-4), 2,4,5,6-Tetraaminopyrimidine Sulfate (CAS 5392-28-9), 4-(Methylamino)benzoic Acid (CAS 10541-83-0), 2,4-Diamino-6-(hydroxymethyl)pteridine (CAS 945-24-4), 6-(Chloromethyl)pteridine-2,4-diamine HCl (CAS 82778-08-3), N-[4-(Methylamino)benzoyl]-L-glutamic Acid Zinc Salt (CAS 66104-81-2), and Methotrexate Disodium Salt Crude (CAS 7413-34-5).

Purity / Assay: Controlled Quality Grades
Appearance: Fine Crystalline / Salt Form
COA CoA per Intermediate Lot Process Support

Why Source Oncology Intermediates Through Pharmabridge?

Technical Match

We verify your exact pharmacopeial grade, assay requirements, mesh size, and impurity limits.

Regulatory Support

Full audit documentation, COA, MOA, Stability Data, and DMF compliance packages.

Reliable Logistics

Cold chain and temperature-monitored shipping options for sensitive active compounds.